Apparent kurtosis and fractional anisotropy potentially predicts tissue outcome in sub-acute stroke
نویسندگان
چکیده
Introduction In acute to early subacute middle cerebral arterial stroke, the mean diffusivity (MD) is more reduced in white matter (WM) than in gray matter (GM) [1]. Moreover, the temporal evolution of MD and fractional anisotropy (FA) is different for WM and GM with varying degree of WM damage at three months [2]. The apparent diffusion kurtosis (ADK) has previously been proposed for visualization of non-Gaussian diffusion [3]. Changes in kurtosis, determined in repeated diffusion weighted (DW) measurements using different diffusion times (TD), reflect altered micro-structural tissue properties in subacute stroke [4].
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